BDBM50259057 3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one::CHEMBL466068

SMILES CC(C)c1[nH]nc2c1nc(Cc1ccccc1OCCN1CCOCC1)[nH]c2=O

InChI Key InChIKey=DQQIKKSUASWOMX-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50259057   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50:  4.95E+3nMAssay Description:Inhibition of PDE1bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of PDE1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50:  1.13E+3nMAssay Description:Inhibition of PDE1cMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE3aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE3bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE8bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4cMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4dMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE7aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 7B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE7bMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE8aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50259057(3-isopropyl-5-(2-(2-morpholinoethoxy)benzyl)-1H-py...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PDE4aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed