BDBM50259286 8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-3-carboxamide::CHEMBL466921

SMILES NC(=O)C1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccc(F)cc1

InChI Key InChIKey=XOZUPJZIFKSWPZ-UHFFFAOYSA-N

Data  4 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50259286   

TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataKi:  752nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50259286(8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8...)
Affinity DataEC50:  947nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed