BDBM50259286 8-(bis(2-chlorophenyl)methyl)-3-(4-fluorophenyl)-8-azabicyclo[3.2.1]octane-3-carboxamide::CHEMBL466921
SMILES NC(=O)C1(CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl)c1ccc(F)cc1
InChI Key InChIKey=XOZUPJZIFKSWPZ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50259286
Affinity DataKi: 16nMAssay Description:Displacement of [125I][Tyr14]nociceptin from human cloned NOP receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 126nMAssay Description:Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 752nMAssay Description:Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 1.04E+3nMAssay Description:Displacement of [3H]diprenorphine from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Agonist activity at human NOP assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
TargetMu-type opioid receptor(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataEC50: 947nMAssay Description:Agonist activity at human mu opioid assessed as stimulation of GDP-induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair