BDBM50259917 CHEMBL4088682
SMILES COc1ccc2nc(NC3=NCC4(CN5CCC4CC5)N3)sc2c1
InChI Key InChIKey=VQIQZCGEEUIMJL-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50259917
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataEC50: 880nMAssay Description:Agonist activity at alpha7 nAChR (unknown origin) expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Bristol-Myers Squibb Research and Development
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Antagonist activity at 5-HT3A receptor (unknown origin) assessed as decrease in calcium influx by Fluo-4-AM dye based FLIPR assayMore data for this Ligand-Target Pair