BDBM50263057 CHEMBL381230
SMILES CN1C(=O)NC(Cc2c[nH]c3c(Cl)cccc23)C1=O
InChI Key InChIKey=WIKGAEMMNQTUGL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50263057
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant AurKA after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 320nMAssay Description:Inhibition of RIPK1 (1 to 312 residues) (unknown origin) preincubated for 15 mins followed by addition of [gamma32P] ATP and measured after 30 mins b...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Fudan University
Curated by ChEMBL
Fudan University
Curated by ChEMBL
Affinity DataIC50: 754nMAssay Description:Inhibition of human recombinant RIPK1 after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair
Affinity DataIC50: >3.00E+3nMAssay Description:Inhibition of human recombinant AurKB after 4 hrs by ADP-Glo assayMore data for this Ligand-Target Pair