BDBM50263159 CHEMBL4065014

SMILES Cc1cc(Nc2nc(Nc3ccc(NC(=O)C4CC4)cc3)nc(n2)N2CCOCC2)n[nH]1

InChI Key InChIKey=GEWGOGLSSRSKQJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263159   

TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263159(CHEMBL4065014)
Affinity DataIC50:  2.64E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-interacting serine/threonine-protein kinase 1(Mus musculus)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50263159(CHEMBL4065014)
Affinity DataIC50:  1.06E+3nMAssay Description:Inhibition of RIPK1 in mouse L929sA cells transfected with human Fas assessed as inhibition in TNF-induced necroptosis pretreated for 0.5 hrs followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed