BDBM50264285 1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3,5-tetrahydrobenzo[e][1,4]oxazepin-7-yl)-1H-pyrrole-2-carbonitrile::CHEMBL492021

SMILES Cn1c(ccc1-c1ccc2NC(=O)COC(C)(c3cccs3)c2c1)C#N

InChI Key InChIKey=GTAVTWRIXVZPIC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50264285   

TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264285(1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3...)
Affinity DataIC50:  2.40nMAssay Description:Displacement of [3H]progesterone from progesterone receptor in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50264285(1-methyl-5-(5-methyl-2-oxo-5-(thiophen-2-yl)-1,2,3...)
Affinity DataEC50:  0.800nMAssay Description:Activity at progesterone receptor assessed as alkaline phosphatase activity in human T47D cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed