BDBM50269584 CHEMBL4076889

SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(COC(=O)c2cc3ccccc3oc2=O)cc1-c1ccc(F)cc1

InChI Key InChIKey=CJCPRVUKZFMQGA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50269584   

TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269584(CHEMBL4076889)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of COX1 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269584(CHEMBL4076889)
Affinity DataIC50:  6.32E+3nMAssay Description:Inhibition of 5-LOX in Sprague Dawley rat Leukocytes assessed as reduction in calcium ionophore A23187-induced LTB4 production preincubated for 30 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50269584(CHEMBL4076889)
Affinity DataIC50:  3.36E+3nMAssay Description:Inhibition of COX2 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed