BDBM50269584 CHEMBL4076889
SMILES NS(=O)(=O)c1ccc(cc1)-n1nc(COC(=O)c2cc3ccccc3oc2=O)cc1-c1ccc(F)cc1
InChI Key InChIKey=CJCPRVUKZFMQGA-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50269584
Affinity DataIC50: 4.33E+4nMAssay Description:Inhibition of COX1 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 6.32E+3nMAssay Description:Inhibition of 5-LOX in Sprague Dawley rat Leukocytes assessed as reduction in calcium ionophore A23187-induced LTB4 production preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+3nMAssay Description:Inhibition of COX2 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair