BDBM50269586 CHEMBL4077653
SMILES COc1cccc(c1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(=O)OCCOc1cc(=O)oc2ccccc12
InChI Key InChIKey=XHKFFJSTNFVKSY-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50269586
Affinity DataIC50: 5.73E+4nMAssay Description:Inhibition of COX1 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Nanjing University
Curated by ChEMBL
Nanjing University
Curated by ChEMBL
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of 5-LOX in Sprague Dawley rat Leukocytes assessed as reduction in calcium ionophore A23187-induced LTB4 production preincubated for 30 mi...More data for this Ligand-Target Pair
Affinity DataIC50: 430nMAssay Description:Inhibition of COX2 (unknown origin) assessed as reduction in PGE2 level using arachidonic acid as substrate after 5 mins in presence of heme by ELISAMore data for this Ligand-Target Pair