BDBM50271277 1H-Indazole-7-carbonitrile::CHEMBL484298

SMILES N#Cc1cccc2cn[nH]c12

InChI Key InChIKey=QXSXSDGUHOPEDJ-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50271277   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50271277(1H-Indazole-7-carbonitrile | CHEMBL484298)
Affinity DataKi:  1.30E+4nMAssay Description:Activity of rat brain recombinant nNOS assessed as L-arginine oxidation in presence of 10 uM (6R)-5,6,7,8-tetrahydro-L-biopterinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Université

Curated by ChEMBL
LigandPNGBDBM50271277(1H-Indazole-7-carbonitrile | CHEMBL484298)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of bovine recombinant eNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Université

Curated by ChEMBL
LigandPNGBDBM50271277(1H-Indazole-7-carbonitrile | CHEMBL484298)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibition of rat brain recombinant nNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Université

Curated by ChEMBL
LigandPNGBDBM50271277(1H-Indazole-7-carbonitrile | CHEMBL484298)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of mouse recombinant iNOSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed