BDBM50272071 (E/Z)-N-phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol-5-yl)vinyl)pyrimidin-2-amine::CHEMBL526932

SMILES N(c1ccccc1)c1nccc(\C=C\c2c(nc3sccn23)-c2ccccc2)n1

InChI Key InChIKey=BIZISPKHXAZMJW-VAWYXSNFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272071   

TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272071((E/Z)-N-phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272071((E/Z)-N-phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50:  6.80E+4nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272071((E/Z)-N-phenyl-4-(2-(6-phenylimidazo[2,1-b]thiazol...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed