BDBM50272265 (E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vinyl)pyrimidin-2-amine::CHEMBL499891

SMILES Nc1nccc(\C=C\c2c(ncn2Cc2ccccc2)-c2ccccc2)n1

InChI Key InChIKey=VHTDDEQGXAKILP-VAWYXSNFSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50272265   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant KDR (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  3.10E+4nMAssay Description:Inhibition of recombinant Flt1 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50272265((E/Z)-4-(2-(1-benzyl-4-phenyl-1H-imidazol-5-yl)vin...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of recombinant Tie2 (unknown origin) expressed in baculovirus-Sf21 systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed