BDBM50274921 5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole::CHEMBL513258

SMILES Fc1ccc(CC2(CCNC2)c2ccc3[nH]ccc3c2)cc1

InChI Key InChIKey=RBNFIIOAQFISLC-UHFFFAOYSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50274921   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataKi:  7nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataKi:  15nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataKi:  79nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2D6 (unknown origin) by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50274921(5-(3-(4-fluorobenzyl)pyrrolidin-3-yl)-1H-indole | ...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed