BDBM50275440 3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine::CHEMBL486537

SMILES C(c1ccccc1)C1(CCNC1)c1ccc2sccc2c1

InChI Key InChIKey=VVROCSNBKQTQEO-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50275440   

TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataKi:  3nMAssay Description:Inhibition of NET (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataKi:  7nMAssay Description:Inhibition of SERT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataKi:  16nMAssay Description:Inhibition of DAT (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50275440(3-(benzo[b]thiophen-5-yl)-3-benzylpyrrolidine | CH...)
Affinity DataIC50:  1.10E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed