BDBM50280293 3-[4-Allyl-3-tert-butylsulfanyl-1-(4-chloro-benzyl)-5-(quinolin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid::CHEMBL47539

SMILES CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)c(CC=C)c12

InChI Key InChIKey=PFGWMUXRIIXOOD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280293   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50280293(3-[4-Allyl-3-tert-butylsulfanyl-1-(4-chloro-benzyl...)
Affinity DataIC50:  27nMAssay Description:Compound was tested for its binding activity towards 5-lipoxygenase activating protein (FLAP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50280293(3-[4-Allyl-3-tert-butylsulfanyl-1-(4-chloro-benzyl...)
Affinity DataIC50: >8.00E+3nMAssay Description:Compound was tested for its inhibitory activity against 5-lipoxygenase in rat.More data for this Ligand-Target Pair
In DepthDetails Article