BDBM50287163 4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2-[4-(2,3-dimethyl-phenyl)-piperazin-1-yl]-ethyl}-amide::CHEMBL29182

SMILES COc1c(cc(Br)c2ccccc12)C(=O)NCCN1CCN(CC1)c1cccc(C)c1C

InChI Key InChIKey=KQOHKQXMRPXPAM-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50287163   

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287163(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  50nMAssay Description:Binding affinity at Dopamine D3 receptors in rat striatum by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287163(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  50.1nMAssay Description:Competitive inhibition of [3H]spiperone binding to the human dopamine receptor D3 expressed in CHO cells, expressed as 10log KiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287163(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataEC50:  68nMAssay Description:Stimulation of mitogenesis in Dopamine receptor D3 transfected CHO p-5 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article

TargetD(2) dopamine receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50287163(4-Bromo-1-methoxy-naphthalene-2-carboxylic acid {2...)
Affinity DataKi:  1.17E+3nMAssay Description:Binding affinity at Dopamine D2 receptors in rat striatum by [3H]spiperone displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2010
Entry Details Article