BDBM50293268 (1R,3R)-5-((R)-11-hydroxy-7,11-dimethyldodec-2-enylidene)-2-methylenecyclohexane-1,3-diol::CHEMBL456003

SMILES [#6]-[#6@H](-[#6]-[#6]-[#6]\[#6]=[#6]\[#6]=[#6]-1\[#6]-[#6@@H](-[#8])-[#6](=[#6])-[#6@H](-[#8])-[#6]-1)-[#6]-[#6]-[#6]C([#6])([#6])[#8]

InChI Key InChIKey=RIIZEYTUOSUDSC-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50293268   

TargetVitamin D3 receptor(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50293268((1R,3R)-5-((R)-11-hydroxy-7,11-dimethyldodec-2-eny...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]-1alpha,25(OH)2D3 from recombinant rat VDR by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50293268((1R,3R)-5-((R)-11-hydroxy-7,11-dimethyldodec-2-eny...)
Affinity DataKi:  50nMAssay Description:Displacement of [3H]1-alpha,25-(OH)2D3 from rat recombinant full length VDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50293268((1R,3R)-5-((R)-11-hydroxy-7,11-dimethyldodec-2-eny...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at rat VDR in ROS 17/2.8 cells transfected with Cyp24a1 reporter plasmid assessed as increase in Cyp24a1 transcription after 16 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/21/2012
Entry Details Article
PubMed
TargetVitamin D3 receptor(Rat)
University of Wisconsin-Madison

Curated by ChEMBL
LigandPNGBDBM50293268((1R,3R)-5-((R)-11-hydroxy-7,11-dimethyldodec-2-eny...)
Affinity DataEC50:  50nMAssay Description:Activity at VDR in rat ROS 17/2.8 cells assessed as transcriptional activation of 24-hydroxylase gene promoter after 16 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed