BDBM50295381 (2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl]sulfonyl}-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazine::CHEMBL562695

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(cc1Cl)N1CCC(F)CC1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=SXUJMLVZOLOFHO-OAHLLOKOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295381   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295381((2R)-1-{[2-Chloro-4-(4-fluoropiperidin-1-yl)phenyl...)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed