BDBM50299366 4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl)-N-(pyridin-4-yl)-1,3,5-triazin-2-amine::CHEMBL584291

SMILES C1C(Cc2ccccc12)Oc1nc(Nc2ccncc2)nc(n1)N1CCNCC1

InChI Key InChIKey=CBZPYDUOYXRYPL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299366   

TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50:  57nMAssay Description:Inhibition of ROCK1 in human THP1 cells assessed as inhibition of MCP1-induced cell migrationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50299366(4-(2,3-dihydro-1H-inden-2-yloxy)-6-(piperazin-1-yl...)
Affinity DataIC50:  8nMAssay Description:Inhibition of ROCK1 by IMAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed