BDBM50300687 2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol-2-ylamino)-5-methylbenzenesulfonic acid::CHEMBL573503

SMILES Cc1ccc(Nc2nnc(CSc3ccc(Cl)cc3)s2)c(c1)S(O)(=O)=O

InChI Key InChIKey=LFAIDABUOLWUEQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50300687   

TargetPenicillin-binding protein 2x(Streptococcus pneumoniae)
Institut De Biologie Structurale Jean-Pierre Ebel (Cea/Cnrs/Ujf)

Curated by ChEMBL
LigandPNGBDBM50300687(2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol...)
Affinity DataIC50:  2.19E+5nMAssay Description:Inhibition of penicillin-resistant Streptococcus pneumoniae 5204 PBP2X preincubated for 4 hrs before addition of substrate (R)-[2-(benzoylamino)propi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPenicillin-binding protein 2X(Streptococcus pneumoniae R6)
Institut De Biologie Structurale Jean-Pierre Ebel (Cea/Cnrs/Ujf)

Curated by ChEMBL
LigandPNGBDBM50300687(2-(5-((4-chlorophenylthio)methyl)-1,3,4-thiadiazol...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of penicillin-sensitive Streptococcus pneumoniae R6 PBP2X preincubated for 1 hr before addition of substrate (R)-[2-(benzoylamino)propiony...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed