BDBM50302172 (R)-3-amino-6-(3-hydroxypyrrolidin-1-yl)-4-propylthieno[2,3-b]pyridine-2-carboxamide::CHEMBL569011

SMILES CCCc1cc(nc2sc(C(N)=O)c(N)c12)N1CC[C@@H](O)C1

InChI Key InChIKey=RWRAVUPGHCNUIG-SECBINFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50302172   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Homo sapiens (Human))
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50302172((R)-3-amino-6-(3-hydroxypyrrolidin-1-yl)-4-propylt...)
Affinity DataIC50:  1.95E+3nMAssay Description:Inhibition of Flag epitope-tagged IKK-beta preincubated for 5 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed