BDBM50304594 CHEMBL593831::N-[2-Benzoyl-4-(2-naphthoylamino)phenyl]-2-(4-methylpiperazin-1-yl)-2-phenylacetamide

SMILES CN1CCN(CC(=O)Nc2ccc(NC(=O)c3ccc4ccccc4c3)cc2C(=O)c2ccccc2)CC1

InChI Key InChIKey=OHLDWTWMABSEOF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304594   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50304594(CHEMBL593831 | N-[2-Benzoyl-4-(2-naphthoylamino)ph...)
Affinity DataEC50:  480nMAssay Description:Inhibition of ABCB1 overexpressed in human CCRF-CEM/VCR1000 cell assessed as inhibition of daunomycin efflux after 30 mins by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed