BDBM50304596 CHEMBL594910::N-(2-Benzoyl-4-phenylacetylaminophenyl)-2-(4-methylpiperazin-1-yl)-2-phenylacetamide

SMILES CN1CCN(CC(=O)Nc2ccc(NC(=O)CCc3ccccc3)cc2C(=O)c2ccccc2)CC1

InChI Key InChIKey=VYMHIEJMPWXTEV-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50304596   

TargetATP-dependent translocase ABCB1(Homo sapiens (Human))
Philipps-Universit£T Marburg

Curated by ChEMBL
LigandPNGBDBM50304596(CHEMBL594910 | N-(2-Benzoyl-4-phenylacetylaminophe...)
Affinity DataEC50:  2.23E+3nMAssay Description:Inhibition of ABCB1 overexpressed in human CCRF-CEM/VCR1000 cell assessed as inhibition of daunomycin efflux after 30 mins by FACS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed