BDBM50306393 5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dione::CHEMBL598935

SMILES Oc1[nH]c(=O)sc1Cc1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=JTHIOMBKPKGALQ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50306393   

TargetFree fatty acid receptor 1(Human)
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM50306393(5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...)
Affinity DataEC50:  500nMAssay Description:Partial agonist activity at human GPR40 expressed in CHO cells assessed as fatty acid-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Human)
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM50306393(5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...)
Affinity DataEC50:  474nMAssay Description:Agonist activity at human GPR40 expressed in CHO cells assessed as intracellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFree fatty acid receptor 1(Human)
Suez Canal University

Curated by ChEMBL
LigandPNGBDBM50306393(5-(4-(4-fluorophenoxy)benzyl)thiazolidine-2,4-dion...)
Affinity DataEC50:  480nMAssay Description:Agonist activity at human GPR40 by FLIPR assay in presence of 1% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed