BDBM50308680 CHEMBL606239::N-{4-[3-(4-Trimethylsilanylbenzyl)thioureidomethyl]-phenyl}methanesulfonamide

SMILES C[Si](C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)cc2)cc1

InChI Key InChIKey=QKLVIEPOQYTQHX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50308680   

TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308680(N-{4-[3-(4-Trimethylsilanylbenzyl)thioureidomethyl...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as reduction of capsaicin-stimulated intracellular 45Ca2+ influx by scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rat)
Sookmyung Women'S University

Curated by ChEMBL
LigandPNGBDBM50308680(N-{4-[3-(4-Trimethylsilanylbenzyl)thioureidomethyl...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at TRPV1 in Sprague-Dawley rat DRG neuron assessed as intracellular 45Ca2+ influx by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed