BDBM50309351 6,7-dichloro-4-(4-fluoro-3-(4-(pyrrolidin-1-yl)piperidine-1-carbonyl)benzyl)pyrrolo[1,2-a]pyrazin-1(2H)-one::CHEMBL589833

SMILES Fc1ccc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)cc1C(=O)N1CCC(CC1)N1CCCC1

InChI Key InChIKey=CZOIIHSTWAZOKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50309351   

TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309351(6,7-dichloro-4-(4-fluoro-3-(4-(pyrrolidin-1-yl)pip...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Irbm/Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50309351(6,7-dichloro-4-(4-fluoro-3-(4-(pyrrolidin-1-yl)pip...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of PARP1 by topcount microplate scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed