BDBM50309930 6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-tetraaza-tricyclo[11.10.2.0*3,7*]pentacos-10-yl)-hexanoic acid hydroxyamide::CHEMBL592719
SMILES ONC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@@H]2CCCCCCCCCC[C@@H](NC1=O)C(=O)N2
InChI Key InChIKey=BVYNKHHGAJSMBT-CLAROIROSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50309930
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Graduate School Of Life Science And Systems Engineering
Curated by ChEMBL
Affinity DataIC50: 410nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair