BDBM50312543 CHEMBL1076909::N-((1S,2S,4R)-1-Benzyloxymethyl-4-cyclopropylcarbamoyl-2-hydroxy-pentyl)-5-(methanesulfonyl-methyl-amino)-N'-((R)-1-phenyl-ethyl)-isophthalamide

SMILES C[C@H](C[C@H](O)[C@H](COCc1cc(F)cc(F)c1)NC(=O)c1cc(cc(c1)C(=O)N[C@H](C)c1ccccc1)N(C)S(C)(=O)=O)C(=O)NC1CC1

InChI Key InChIKey=RXOLOZUDTSFNAU-RSOAUGTRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50312543   

TargetCathepsin D(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312543(CHEMBL1076909 | N-((1S,2S,4R)-1-Benzyloxymethyl-4-...)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human liver cathepsin D after 20 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Link£Ping University

Curated by ChEMBL
LigandPNGBDBM50312543(CHEMBL1076909 | N-((1S,2S,4R)-1-Benzyloxymethyl-4-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of BACE1 after 30 mins by homogeneous time resolved fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed