BDBM50320351 3-(4-(4-benzoylpiperazin-1-yl)phthalazin-1-yl)benzonitrile::CHEMBL1082386

SMILES O=C(N1CCN(CC1)c1nnc(-c2cccc(c2)C#N)c2ccccc12)c1ccccc1

InChI Key InChIKey=AMQWUBPMEUNWCK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50320351   

TargetSmoothened homolog(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50320351(3-(4-(4-benzoylpiperazin-1-yl)phthalazin-1-yl)benz...)
Affinity DataIC50:  212nMAssay Description:Inhibition of human SMO expressed in HEPM cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed