BDBM50321455 2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thiophene-3-sulfonamide::CHEMBL1172329

SMILES Cc1ccc(cc1)N(SC(Cl)(Cl)Cl)S(=O)(=O)c1cc(Cl)sc1Cl

InChI Key InChIKey=PKAHLRVRIDTYNC-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50321455   

TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of human CDK1/cyclin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50:  1.15E+4nMAssay Description:Inhibition of human CDK2/Cyclin AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMO15-related protein kinase Pfmrk(Plasmodium falciparum)
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50:  300nMAssay Description:Inhibition of His6x-tagged Plasmodium falciparum Pfmrk expressed in Escherichia coli by microtiter plate scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 6/G1/S-specific cyclin-D1(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human CDK6/Cyclin D1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-H/Cyclin-dependent kinase 7(Homo sapiens (Human))
Walter Reed Army Institute Of Research

Curated by ChEMBL
LigandPNGBDBM50321455(2,5-dichloro-N-p-tolyl-N-(trichloromethylthio)thio...)
Affinity DataIC50:  700nMAssay Description:Inhibition of human CDK7/Cyclin H/MAT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed