BDBM50324277 (Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-2-oxoindolin-5-yl]benzenesulfonamide::CHEMBL1215346
SMILES CN(C)CCCc1c(C=C2C(=O)Nc3ccc(NS(=O)(=O)c4ccccc4)cc23)[nH]c2CCCC(=O)c12
InChI Key InChIKey=VMUAYDSPKYLLJV-UHFFFAOYSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50324277
Affinity DataIC50: 235nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of CSF1R by radiometric methodMore data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of PDGFRbeta by radiometric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of VEGFR2 by radiometric methodMore data for this Ligand-Target Pair
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of FLT3 by radiometric methodMore data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Development Center For Biotechnology
Curated by ChEMBL
Development Center For Biotechnology
Curated by ChEMBL
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of c-Kit by radiometric methodMore data for this Ligand-Target Pair