BDBM50324277 (Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6,7-tetrahydro-1H-indol-2-yl}methylene)-2-oxoindolin-5-yl]benzenesulfonamide::CHEMBL1215346

SMILES CN(C)CCCc1c(C=C2C(=O)Nc3ccc(NS(=O)(=O)c4ccccc4)cc23)[nH]c2CCCC(=O)c12

InChI Key InChIKey=VMUAYDSPKYLLJV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50324277   

TargetAurora kinase B(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50:  235nMAssay Description:Inhibition of recombinant aurora BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of CSF1R by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of PDGFRbeta by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50:  2.19E+3nMAssay Description:Inhibition of recombinant aurora AMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of VEGFR2 by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of FLT3 by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Development Center For Biotechnology

Curated by ChEMBL
LigandPNGBDBM50324277((Z)-N-[3-({3-[3-(Dimethylamino)propyl]-4-oxo-4,5,6...)
Affinity DataIC50: <1.00E+3nMAssay Description:Inhibition of c-Kit by radiometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed