BDBM50326068 (E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylthio)-1-(4-fluorophenyl)prop-2-en-1-one::CHEMBL1242760

SMILES [O-][N+](=O)c1cc(\C=C(\SCc2ccc(F)cc2)C(=O)c2ccc(F)cc2)ccc1F

InChI Key InChIKey=MUMWSXHTWWVJHP-CIAFOILYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50326068   

TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
Temple University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50326068((E)-3-(4-Fluoro-3-nitrophenyl)-2-(4-fluorobenzylth...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of BCR/ABL p210 autophosphorylation in human K562 cells after 2 hrs by Western blot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed