BDBM50327333 5-methoxy-2-(3-methyl-4-(quinoxalin-6-yl)-1-o-tolyl-1H-pyrazol-5-ylamino)benzoic acid::CHEMBL1258170

SMILES COc1ccc(Nc2c(c(C)nn2-c2ccccc2C)-c2ccc3nccnc3c2)c(c1)C(O)=O

InChI Key InChIKey=MCOJHKJMTCBWSD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50327333   

TargetAdenosine receptor A1(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50327333(5-methoxy-2-(3-methyl-4-(quinoxalin-6-yl)-1-o-toly...)
Affinity DataIC50: 3.20nMAssay Description:Antagonist activity at adenosine A1 receptor by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50327333(5-methoxy-2-(3-methyl-4-(quinoxalin-6-yl)-1-o-toly...)
Affinity DataIC50: 1.30E+4nMAssay Description:Antagonist activity at adenosine A3 receptor by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50327333(5-methoxy-2-(3-methyl-4-(quinoxalin-6-yl)-1-o-toly...)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at adenosine A2A receptor by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Bayer Schering Pharma

Curated by ChEMBL
LigandPNGBDBM50327333(5-methoxy-2-(3-methyl-4-(quinoxalin-6-yl)-1-o-toly...)
Affinity DataIC50: 5.00E+4nMAssay Description:Antagonist activity at adenosine A2B receptor by cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMed