BDBM50332459 ((2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate::CHEMBL1630001

SMILES C[C@@]1(F)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1n1cnc2c1nc(N)[nH]c2=O

InChI Key InChIKey=GFEXCNGIPRYQFE-GITKWUPZSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50332459   

TargetRNA-directed RNA polymerase(Hepatitis C virus)
Janssen Biopharma

Curated by ChEMBL
LigandPNGBDBM50332459(((2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataIC50:  99nMAssay Description:Inhibition of HCV NS5B RNA-dependent RNA polymerase activity assessed as reduction in radiolabeled ribonucleotide monophosphates incorporation into R...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNS5B(Hepatitis C virus)
Pharmasset

Curated by ChEMBL
LigandPNGBDBM50332459(((2R,3R,4R,5R)-5-(2-amino-6-oxo-1H-purin-9(6H)-yl)...)
Affinity DataIC50:  5.94E+3nMAssay Description:Inhibition of HCV NS5B polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed