BDBM50332480 4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-2-oxo-2H-chromen-3-yl)methyl)-butanoic acid hydroxyamide::CHEMBL1630091

SMILES CCN(CC)CCOc1ccc(CCC(Cc2cc3ccc(C)cc3oc2=O)C(=O)NO)cc1

InChI Key InChIKey=UNOIUBNRWWBQDJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50332480   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50332480(4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-...)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human MMP9 in cell-free system by fluorescent spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50332480(4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of human TNF-alpha by fluorescent spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50332480(4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-...)
Affinity DataIC50:  8.70E+3nMAssay Description:Inhibition of human MMP3 in cell-free system by fluorescent spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50332480(4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-...)
Affinity DataIC50:  5.57E+5nMAssay Description:Inhibition of human MMP1 in cell-free system by fluorescent spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Yonsei University

Curated by ChEMBL
LigandPNGBDBM50332480(4-(4-(2-(Diethylamino)ethoxy)phenyl)-2-((7-methyl-...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human TACE by fluorescent spectroscopyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed