BDBM50333437 3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)azetidine::CHEMBL1645604

SMILES Cc1cccc(Cl)c1Oc1cccc(F)c1OC1CNC1

InChI Key InChIKey=VHKIHYNCEPOAKX-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50333437   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333437(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333437(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)
Affinity DataKi:  433nMAssay Description:Displacement of [3H]nisoxetine from human NET by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333437(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)
Affinity DataKi: >4.61E+3nMAssay Description:Displacement of [3H]citalopram from human SERT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50333437(3-(2-(2-chloro-6-methylphenoxy)-6-fluorophenoxy)az...)
Affinity DataKi: >6.41E+3nMAssay Description:Displacement of [3H]WIN-35,428 from human DAT by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed