BDBM50333848 (R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1643787

SMILES CCCCCN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)S(=O)(=O)c1ccc(F)cc1

InChI Key InChIKey=TWVFYVBKIHXAPO-LJQANCHMSA-N

Data  3 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50333848   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333848((R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,...)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human recombinant CRTH2 receptor by cell based radioligand equilibrium competition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333848((R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,...)
Affinity DataKi:  904nMAssay Description:Binding affinity to thromboxane receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333848((R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,...)
Affinity DataKi:  1.21E+3nMAssay Description:Binding affinity to prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333848((R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,...)
Affinity DataIC50:  107nMAssay Description:Antagonist activity at CRTH2 receptor in human whole blood assessed as inhibition of DK-PGD2-induced eosinophils shape changeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50333848((R)-2-(7-(4-fluoro-N-pentylphenylsulfonamido)-6,7,...)
Affinity DataIC50:  4.90nMAssay Description:Antagonist activity at human recombinant CRTH2 receptor expressed in HEK293 cells assessed as inhibition of DK-PGD2-induced intracellular cAMP format...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed