BDBM50334407 10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tetrahydro-5H-1,4,7,10a-tetraaza-cyclohepta[f]indene::CHEMBL1643855

SMILES C1C(CN1c1c2CCNCCc2nc2ccnn12)Oc1ccccn1

InChI Key InChIKey=ZKNSCPDFVLIXAH-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50334407   

Target5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  706nMAssay Description:Agonist activity at human recombinant 5HT2B receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Evotec

Curated by ChEMBL
LigandPNGBDBM50334407(10-[3-(Pyridin-2-yloxy)-azetidin-1-yl]-6,7,8,9-tet...)
Affinity DataEC50:  5.17E+3nMAssay Description:Agonist activity at human recombinant 5HT2A receptor expressed in CHOK1 cells assessed as induction of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed