BDBM50334920 (R)-1-(3,4-dichlorophenyl)-N,N-dimethyl-1,2,3,4-tetrahydroquinolin-4-amine::CHEMBL1643514
SMILES CN(C)[C@@H]1CCN(c2ccc(Cl)c(Cl)c2)c2ccccc12
InChI Key InChIKey=UEPBVWIBDNMJPA-MRXNPFEDSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 50334920
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Sunovion Pharmaceuticals
Curated by ChEMBL
Sunovion Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
Affinity DataIC50: 6.02E+3nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair