BDBM50334925 (S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydroquinolin-3-amine::CHEMBL1643518

SMILES CN[C@@H]1CN(c2ccc(Cl)c(Cl)c2)c2ccccc2C1

InChI Key InChIKey=VNSMQTHLCZBNAH-LBPRGKRZSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50334925   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  128nMAssay Description:Inhibition of human recombinant 5HT transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Sunovion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50334925((S)-1-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrah...)
Affinity DataIC50:  1.25E+3nMAssay Description:Inhibition of human recombinant norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed