BDBM50338118 3,5-dimethyl-N-(3-(6-methyl-1H-indol-2-yl)-1H-indazol-5-yl)isoxazole-4-sulfonamide::CHEMBL1684523

SMILES Cc1noc(C)c1S(=O)(=O)Nc1ccc2[nH]nc(-c3cc4ccc(C)cc4[nH]3)c2c1

InChI Key InChIKey=JJLKCRKCPULHMV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50338118   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Nycomed

Curated by ChEMBL
LigandPNGBDBM50338118(3,5-dimethyl-N-(3-(6-methyl-1H-indol-2-yl)-1H-inda...)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant GST-tagged full-length ITK expressed in baculovirus expression system after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed