BDBM50338158 2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno[2,3-b]pyrrol-4-yl)acetic acid::CHEMBL1684727

SMILES Cc1c(CC(O)=O)c2ccsc2n1Cc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=JSACRWFTEDWZRX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50338158   

TargetProstaglandin D2 receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50: 50nMAssay Description:Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50: 130nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CHO/Ga16 cells co-expressing Galpha16 protein assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50: 3.10E+4nMAssay Description:Displacement of [3H]Dofetilide from human CRTH2 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50338158(2-(5-methyl-6-(4-(methylsulfonyl)benzyl)-6H-thieno...)
Affinity DataIC50: 5.00E+4nMAssay Description:Displacement of [3H]PGD2 from human DP1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2011
Entry Details Article
PubMed