BDBM50339761 CHEMBL1689109::[4-Chloro-2-[4-(phenylsulfonyl)-1-piperazinylmethyl]phenoxy]-acetic acid

SMILES OC(=O)COc1ccc(Cl)cc1CN1CCN(CC1)S(=O)(=O)c1ccccc1

InChI Key InChIKey=VEDPQGGGGHKSLY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50339761   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339761(CHEMBL1689109 | [4-Chloro-2-[4-(phenylsulfonyl)-1-...)
Affinity DataIC50:  16nMAssay Description:Displacement of [3H]PGD2 from human CRTh2 receptor expressed in HEK293 cells after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50339761(CHEMBL1689109 | [4-Chloro-2-[4-(phenylsulfonyl)-1-...)
Affinity DataIC50:  201nMAssay Description:Antagonist activity against human CRTh2 receptor expressed in CHO cells assessed as inhibition of PGD2-mediated Ca2+ fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed