BDBM50342597 (E)-methyl 4-((4-chloro-2-oxo-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-1-yl)methyl)benzoate::CHEMBL1770537

SMILES COC(=O)c1ccc(CN2C(=O)\C(=C\C(=O)c3cccnc3)c3c2cccc3Cl)cc1

InChI Key InChIKey=KZURVWNQVDRESW-LDADJPATSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342597   

TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342597((E)-methyl 4-((4-chloro-2-oxo-3-(2-oxo-2-(pyridin-...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Homo sapiens (Human))
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342597((E)-methyl 4-((4-chloro-2-oxo-3-(2-oxo-2-(pyridin-...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed