BDBM50344217 2-[3-[2-[5-Methyl-2-phenyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yloxy]-2-methylpropionic acid::CHEMBL1778732

SMILES Cc1oc(nc1CCc1noc2cc(OC(C)(C)C(O)=O)ccc12)-c1ccccc1

InChI Key InChIKey=FZKFOUPDFQAVGI-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344217   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344217(2-[3-[2-[5-Methyl-2-phenyl-4-oxazolyl]ethyl]-1,2-b...)
Affinity DataEC50:  1.29E+4nMAssay Description:Agonist activity at human PPARalpha-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344217(2-[3-[2-[5-Methyl-2-phenyl-4-oxazolyl]ethyl]-1,2-b...)
Affinity DataEC50:  1.49E+4nMAssay Description:Agonist activity at human PPARdelta-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344217(2-[3-[2-[5-Methyl-2-phenyl-4-oxazolyl]ethyl]-1,2-b...)
Affinity DataEC50:  2.08E+4nMAssay Description:Agonist activity at human PPARgamma-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed