BDBM50344226 2-[3-[2-[2-(4-tert-Butylphenyl)-5-isopropyl-4-oxazolyl]ethyl]-1,2-benzisoxazol-6-yloxy]-2-methylpropionic acid::CHEMBL1778835

SMILES CC(C)c1oc(nc1CCc1noc2cc(OC(C)(C)C(O)=O)ccc12)-c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=MIGZFASXXKNXJR-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344226   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344226(2-[3-[2-[2-(4-tert-Butylphenyl)-5-isopropyl-4-oxaz...)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human PPARgamma-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344226(2-[3-[2-[2-(4-tert-Butylphenyl)-5-isopropyl-4-oxaz...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human PPARdelta-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Nippon Chemiphar

Curated by ChEMBL
LigandPNGBDBM50344226(2-[3-[2-[2-(4-tert-Butylphenyl)-5-isopropyl-4-oxaz...)
Affinity DataEC50:  2.90E+3nMAssay Description:Agonist activity at human PPARalpha-LBD expressed in CV1 cells co-transfected with Gal4 after 40 hrs by luciferase based transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed