BDBM50344654 8-(2-(diethylamino)ethoxy)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile::CHEMBL1779192

SMILES CCN(CC)CCOc1ccc2C(=O)c3c([nH]c4cc(ccc34)C#N)C(C)(C)c2c1

InChI Key InChIKey=BEDSGOCODTYQEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344654   

TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50344654(8-(2-(diethylamino)ethoxy)-6,6-dimethyl-11-oxo-6,1...)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetALK tyrosine kinase receptor(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50344654(8-(2-(diethylamino)ethoxy)-6,6-dimethyl-11-oxo-6,1...)
Affinity DataIC50: 8nMAssay Description:Inhibition of ALK assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed