BDBM50345187 4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzonitrile::CHEMBL255108

SMILES O=C1CC(Oc2c1ccc1ccccc21)c1ccc(cc1)C#N

InChI Key InChIKey=LIUTUDSSIWWZTA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345187   

TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50345187(4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzo...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human aromatase in placental microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Upres Ea 4021 Biomol�Cules Et Th�Rapies Anti-Tumorales

Curated by ChEMBL
LigandPNGBDBM50345187(4-(4-oxo-3,4-dihydro-2H-benzo[h]chromen-2-yl)benzo...)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of aromatase in human placental microsomes assessed as inhibition of aromatization of [1,2,6,7-3H] androstenedione by flow scintillation a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed