BDBM50350760 CHEMBL1818436

SMILES OC[C@@H]1NCC[C@@H](O)[C@H]1O

InChI Key InChIKey=YZNNBIPIQWYLDM-JKUQZMGJSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50350760   

TargetLactase/phlorizin hydrolase(Rattus norvegicus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50:  1.22E+5nMAssay Description:Inhibition of rat intestinal lactase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50:  2.25E+5nMAssay Description:Inhibition of rat intestinal sucrase assessed as production of p-nitrophenol at by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-lysosomal glucosylceramidase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of glucosylceramidase 2 from spleen of patient with gaucher's disease by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue alpha-L-fucosidase(Bos taurus)
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50:  2.60E+5nMAssay Description:Inhibition of bovine epididymis alpha-L-fucosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
TBA

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-galactosidase(Bos taurus (Bovine))
University Of Toyama

Curated by ChEMBL
LigandPNGBDBM50350760(CHEMBL1818436)
Affinity DataIC50:  9.60E+5nMAssay Description:Inhibition of bovine liver beta-galactosidase assessed as production of p-nitrophenol by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed