BDBM50353181 CHEMBL1829485

SMILES C[C@H](COc1ccc(cc1)-c1ccc(=O)n(C)n1)CN1CCC[C@H]1C

InChI Key InChIKey=VHKZHZYOGPESQF-JKSUJKDBSA-N

Data  2 KI  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50353181   

TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]NAMH from human cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Rattus norvegicus (rat))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]NAMH from rat cloned histamine 3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H3 receptor(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataEC50:  2.10nMAssay Description:Antagonist activity at human histamine 3 receptor by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Cephalon

Curated by ChEMBL
LigandPNGBDBM50353181(CHEMBL1829485)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed