BDBM50358373 CHEMBL1922839
SMILES CCCOc1cc(cc2n(Cc3ccc(cc3)C(=O)Nc3nnn[nH]3)c(=Nc3ccc(cc3)C(C)(C)C)n(C)c12)C(F)(F)F
InChI Key InChIKey=LOKUGNIDKBRXJC-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50358373
TargetGlucagon-like peptide 1 receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human GLP1 receptor by cAMP assayMore data for this Ligand-Target Pair
TargetGastric inhibitory polypeptide receptor(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of human GIP receptor by cAMP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cells after 4 to 12 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human GCGR expressed in CHO cells assessed as inhibition of glucagon-induced [125I]cAMP accumulation after 30 mins by scintill...More data for this Ligand-Target Pair